Piperazine – Kyron

The Piperazine Salts are used for the treatment of ascarids in poultry.

Kyron’s Piperazine is a white crystalline powder consisting of 100% piperazine adipate (=37% piperazine base).

Piperazine acts by altering muscular polirasation in susceptible nematodes, thereby paralysing the worm and allowing it to be passed out with the faeces. This neuromuscular effect is believed to result from blocking acetylcholine at the myoneural junction. In ascarids, succinic acid production is also inhibited.

Piperazine Adipate is readily absorbed from the proximal sections of the GI tract, and the drug is metabolised and excreted by the kidneys.

INDICATIONS

Poultry: Round Worms (Ascaridis galli, Capillaria Spp.)

DOSAGE

Adult Birds: 15 g for 30 adult birds (0,5 g / kg body weight)*
Below 6 weeks: 15 g for 60 birds (0,25 g / kg body weight) in feed or drinking water. When infestation with Capillaria species is suspected, double the recommended dose.

To poultry the substance is given in each of 2 successive feedings or in drinking water for 2 days (treatment can be repeated 7-10 days later).

*Dosing tips: if a 1 kg bird eats/drinks:
50 g of food, the dose is 10 g / 1 kg feed
160 ml of water, the dose is 10 g / 3 L water

WITHDRAWAL PERIODS

1) Meat withdrawal period: 8 days
2) Eggs withdrawal period: 4 days

STORAGE
Store in a cool (not more than 25 °C), dry place.

PACKAGING
100 g, 500 g, 1 kg

REGISTRATION NUMBER
G1931 Act36/1947